If you are one of the millions of diabetics and have been prescribed Actos, you might want to talk with your doctor and consider changing to another drug. Better yet, get started on a lifestyle modification program. Consider reading Mark Hyman’s book, “The Blood Sugar Solution“, see a knowledgeable doctor, and manage or get rid of your blood sugar issues. Thanks to Alanna Ritchie and drugwatch.com for this article.
Every day around the world, people are prescribed Actos — a drug that treats type 2 diabetes.
What some of them don’t know is that the popular medication — which grossed more than $4.6 billion in 2010 — carries with it an increased risk for congestive heart failure (CHF). CHF means the heart is not pumping strongly enough.
People with diabetes may also be dealing with heart disease and high blood pressure, which both can lead to CHF. The primary ways Actos causes CHF is through weight gain and edema, which occurs when fluid builds up in the body.
A Kaiser Permanente Northwest study showed that 7.7 percent of 9,591 diabetes patients developed CHF during a 30-month follow-up period after taking Actos.
Symptoms include chest pain; shortness of breath; fatigue; swelling in the abdomen, legs or feet; rapid heart rate; and a persistent cough. Doctors can use a chest X-ray, electrocardiogram (ECG) or echocardiogram to check for heart failure.
Because of the dangers associated with Actos, the Food and Drug Administration (FDA) has added multiple warnings to the drug’s label concerning Actos side effects.
2000: The label says patients with the functional classification of 3 and 4 heart failure should not take Actos.
2004: The label is strengthened to warn patients that Actos increases the risk of cancer and DNA damage.
2007: The label adds a black-box warning to tell patients that Actos increases the risk of heart failure.
Before prescribing Actos, the American Heart Association and American Diabetes Association recommend that doctors should:
- Check for evidence of underlying cardiac disease.
- Check if patient is taking drugs that may increase fluid retention.
- Check if patient has shortness of breath due cardiac disease.
- Check most recent patient ECG which can show risk factors for CHF.
- Check if patient knows to report symptoms like weight gain, shortness of breath or fatigue.
In 2011, studies revealed that Actos also leads to an increased risk of Actos bladder cancer. Right after, Germany and France stopped selling Actos, but the FDA has chosen to wait and see what future studies reveal.
Alanna Ritchie is a writer for Drugwatch.com. An English major, she is an accomplished technical and creative writer.
Real wonderful information can be found on this site.
[I don’t think I have a case for you,just shared activism against Lilly]
Actos is produced by Takeda Industries and co-marketed by Eli Lilly. Eli Lilly Zyprexa can *cause* diabetes.
I took Zyprexa olanzapine a powerful Lilly schizophrenic drug for 4 years it was prescribed to me off-label for post traumatic stress disorder was ineffective costly and gave me diabetes. Eli Lilly’s #1 cash cow Zyprexa drug sale $65 billion dollars so far,has a ten times greater risk of causing type 2 diabetes over the non-user of Zyprexa. So,here we have a conflict of interest that this same company Eli Lilly also is a big profiteer of diabetes treatment. (Actos works as an insulin *sensitizer*)
Sooooo,Eli Lilly pushes a drug (Zyprexa) that can cause diabetes…. then turn around sell you the drugs (Actos) to treat the diabetes that in turn can cause cancer! What a terrible conflict of interest!
— Daniel Haszard FMI http://www.zyprexa-victims.com
Unfortunately many drugs are prescribed without full awareness of long term side effects. Diabetes is now a well known consequence of Zyprexa. I think our best defense is to eat a diet consisting of real food, without chemicals, and follow a lifestyle that includes plenty of physical activity. There are ways to deal with PTSD. Please consider reading “Unstuck” by James Gordon. He also has a website called http://www.cmbm.org (Center for Mind Body Medicine). His work with victims of Gaza, Hurricane Katrina, and more is inspiring and amazing.